---
title: "Sign System -E22 Annihilation Sequence-"
description: "Read about Sign System -E22 Annihilation Sequence- visual novel."
image: "https://t.vndb.org/cv/21/58721.jpg"
---

# Sign System -E22 Annihilation Sequence-

![Sign System -E22 Annihilation Sequence-](https://t.vndb.org/cv/21/58721.jpg)

**Developer:** C2 Kikan

**Release date:** Dec 31, 2010

**Platform:** Windows

**Language:** Japanese, Chinese (simplified)

**Rating:** 6.5/10 (avg, 1 votes)

## Shops
- [Official Website](http://www.c2architecture.com/E22.html)

## Releases
### Japanese
- **2010-12-31**: Sign System -E22 Annihilation Sequence- - [Official website](http://www.c2architecture.com/E22.html), [ErogameScape](https://erogamescape.dyndns.org/~ap2/ero/toukei_kaiseki/game.php?game=29432)

### Chinese (simplified)
- **2025-09-29**: SignSystem E22 - [Official website](https://github.com/moyu15645/patch/blob/main/SignSystem%20E22.zip)

## Tags
Bloody Scenes, ADV

## More Games from C2 Kikan
- [Sign System -E22 Annihilation Sequence-](https://pinovel.net/v37855)

---
*View the full details at [pinovel.net/v37855](https://pinovel.net/v37855).*

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```