---
title: "Mukatsuku Imouto o Kusuri de Nemurasete Itazura Shite Yatta"
description: "Little sister Karina is always insulting her big brother, who responds finally by putting a roofie in her juice.  [From DLsite English]"
image: "https://t.vndb.org/cv/52/54452.jpg"
---

# Mukatsuku Imouto o Kusuri de Nemurasete Itazura Shite Yatta

![Mukatsuku Imouto o Kusuri de Nemurasete Itazura Shite Yatta](https://t.vndb.org/cv/52/54452.jpg)

**Alternative Title:** ムカつく妹を薬で眠らせてイタズラしてやった

**Aliases:** Precocious Karina and the Comatose Sex

**Developer:** Kurotsukidou

**Release date:** Sep 4, 2014

**Platform:** Windows

**Language:** Japanese

## Description
Little sister Karina is always insulting her big brother, who responds finally by putting a roofie in her juice.

[From [DLsite English](https://www.dlsite.com/maniax/work/=/product_id/RJ139310.html/?locale=en_US)]

## Characters
### Karina (香里奈)
- **Gender:** Female
- **Role:** Full Sister, Younger Sister

## Shops
- [DLsite](https://www.dlsite.com/maniax/work/=/product_id/RJ139310.html)

## Releases
### Japanese
- **2014-09-04**: Mukatsuku Imouto o Kusuri de Nemurasete Itazura Shite Yatta - [DLsite](https://www.dlsite.com/maniax/work/=/product_id/RJ139310.html)

## Tags
Sexual Content, Male Protagonist, Only Protagonist's Sisters as Heroine(s), Only Younger Heroines, Protagonist's Younger Sister as a Heroine, Only Blood-related Heroines

## More Games from Kurotsukidou
- [Mukatsuku Imouto o Kusuri de Nemurasete Itazura Shite Yatta](https://pinovel.net/v34590)

---
*View the full details at [pinovel.net/v34590](https://pinovel.net/v34590).*

```json
{"@context":"https://schema.org","@type":"VideoGame","@id":"https://pinovel.net/v34590#game","name":"Mukatsuku Imouto o Kusuri de Nemurasete Itazura Shite Yatta","description":"Little sister Karina is always insulting her big brother, who responds finally by putting a roofie in her juice.  [From DLsite English]","url":"https://pinovel.net/v34590","image":"https://t.vndb.org/cv/52/54452.jpg","author":{"@type":"Organization","name":"Kurotsukidou"}}
```